Which potential complication is associated with rheumatoid arthritis?

Rheumatoid arthritis (RA) is known to have systemic effects beyond joint inflammation and pain. One significant complication associated with RA is an increased risk of cardiovascular disease. This is due to several factors related to the disease itself. Chronic inflammation in rheumatoid arthritis can lead to endothelial dysfunction, which affects blood vessel health and can promote atherosclerosis, the process of plaque buildup in arteries.

Patients with RA may also experience increased levels of inflammatory markers that contribute to cardiovascular risk, such as C-reactive protein (CRP). Furthermore, lifestyle factors commonly seen in individuals with RA, such as reduced physical activity due to pain and joint limitations, can exacerbate cardiovascular risk.

While osteoporosis and dyslipidemia can also be concerns for patients with RA, the link between chronic inflammation from rheumatoid arthritis and heightened cardiovascular disease risk is well-documented, making it a significant complication of the condition. Kidney stones, while painful and problematic, are not directly associated with the systemic effects of RA.