What prescribed order is least likely to cause adverse effects?

Choosing diclofenac 1% gel is least likely to cause adverse effects primarily due to its topical application form, which limits systemic absorption and consequently minimizes systemic side effects compared to other options. Topical nonsteroidal anti-inflammatory drugs (NSAIDs) like diclofenac are specifically designed to target localized pain and inflammation, allowing effective pain relief with a significantly reduced risk of systemic issues, such as gastrointestinal complications, renal impairment, or cardiovascular risks often associated with systemic NSAIDs.

In contrast, intravenous morphine, while effective for severe pain, can lead to significant side effects such as respiratory depression, sedation, and dependency, especially with long-term use. Oral corticosteroids, though effective anti-inflammatory agents, carry risks such as immunosuppression, weight gain, and increased blood sugar levels, contributing to a variety of metabolic and psychological effects. Intramuscular antibiotics may also have side effects, including allergic reactions, local reactions at the injection site, and potential for systemic side effects especially if there is sensitivity to the antibiotic.

Overall, the localized use of diclofenac gel permits a lower risk profile, making it a safer option in terms of adverse effects when compared to the systemic routes and broad effects of the other medications listed.